Reaction Details Report a problem with these data
Target
Fatty acid-binding protein, heart
Ligand
BDBM50152880
Substrate
n/a
Meas. Tech.
ChEMBL_306241 (CHEMBL830338)
IC50
17000±n/a nM
Citation
 Ringom, R; Axen, E; Uppenberg, J; Lundbäck, T; Rondahl, L; Barf, T Substituted benzylamino-6-(trifluoromethyl)pyrimidin-4(1H)-ones: a novel class of selective human A-FABP inhibitors. Bioorg Med Chem Lett 14:4449-52 (2004) [PubMed]  Article 
Target
Name:
Fatty acid-binding protein, heart
Synonyms:
FABP11 | FABP3 | FABPH_HUMAN | Fatty acid binding protein muscle | MDGI
Type:
PROTEIN
Mol. Mass.:
14858.36
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1463784
Residue:
133
Sequence:
MVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTHGTAVCTRTYEKEA
  
Inhibitor
Name:
BDBM50152880
Synonyms:
2-(4-Methoxy-benzylsulfanyl)-6-trifluoromethyl-pyrimidin-4-ol | CHEMBL184136
Type:
Small organic molecule
Emp. Form.:
C13H11F3N2O2S
Mol. Mass.:
316.299
SMILES:
COc1ccc(CSc2nc(cc(=O)[nH]2)C(F)(F)F)cc1
Structure:
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