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Target
Cytoplasmic protein NCK1
Ligand
BDBM14322
Substrate
n/a
Meas. Tech.
ChEMBL_304472 (CHEMBL832688)
EC50
150000±n/a nM
Citation
 Inglis, SR; Stojkoski, C; Branson, KM; Cawthray, JF; Fritz, D; Wiadrowski, E; Pyke, SM; Booker, GW Identification and specificity studies of small-molecule ligands for SH3 protein domains. J Med Chem 47:5405-17 (2004) [PubMed]  Article 
Target
Name:
Cytoplasmic protein NCK1
Synonyms:
NCK | NCK1 | NCK1_HUMAN | Nck adaptor protein 1
Type:
PROTEIN
Mol. Mass.:
42863.46
Organism:
Homo sapiens (Human)
Description:
ChEMBL_304472
Residue:
377
Sequence:
MAEEVVVVAKFDYVAQQEQELDIKKNERLWLLDDSKSWWRVRNSMNKTGFVPSNYVERKNSARKASIVKNLKDTLGIGKVKRKPSVPDSASPADDSFVDPGERLYDLNMPAYVKFNYMAEREDELSLIKGTKVIVMEKCSDGWWRGSYNGQVGWFPSNYVTEEGDSPLGDHVGSLSEKLAAVVNNLNTGQVLHVVQALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWWKCRKINGMVGLVPKNYVTVMQNNPLTSGLEPSPPQCDYIRPSLTGKFAGNPWYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQLKETVYCIGQRKFSTMEELVEHYKKAPIFTSEQGEKLYLVKHLS
  
Inhibitor
Name:
BDBM14322
Synonyms:
2-Aminoquinoline 1 | 2-aminoquinoline | CHEMBL61236 | Fragment 19 | Quinolin-2-amine | fragment 2 (J. med. chem.,50,1116)
Type:
Small organic molecule
Emp. Form.:
C9H8N2
Mol. Mass.:
144.1732
SMILES:
Nc1ccc2ccccc2n1
Structure:
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