Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM50157672
Substrate
n/a
Meas. Tech.
ChEMBL_430069 (CHEMBL918671)
Ki
82±n/a nM
Citation
 Chang, LC; Spanjersberg, RF; von Frijtag Drabbe Künzel, JK; Mulder-Krieger, T; van den Hout, G; Beukers, MW; Brussee, J; Ijzerman, AP 2,4,6-trisubstituted pyrimidines as a new class of selective adenosine A1 receptor antagonists. J Med Chem 47:6529-40 (2004) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM50157672
Synonyms:
CHEMBL222474 | N-(2,6-diphenylpyrimidin-4-yl)propionamide
Type:
Small organic molecule
Emp. Form.:
C19H17N3O
Mol. Mass.:
303.3578
SMILES:
CCC(=O)Nc1cc(nc(n1)-c1ccccc1)-c1ccccc1
Structure:
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