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Target
Somatostatin receptor type 4
Ligand
BDBM50159410
Substrate
n/a
Meas. Tech.
ChEMBL_306615 (CHEMBL829075)
IC50
>1000±n/a nM
Citation
 Erchegyi, J; Hoeger, CA; Low, W; Hoyer, D; Waser, B; Eltschinger, V; Schaer, JC; Cescato, R; Reubi, JC; Rivier, JE Somatostatin receptor 1 selective analogues: 2. N(alpha)-Methylated scan. J Med Chem 48:507-14 (2005) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 4
Synonyms:
SOMATOSTATIN SST4 | SS-4-R | SS4-R | SS4R | SSR4_HUMAN | SST4R | SSTR4 | Somatostatin receptor type 4 (SSTR4)
Type:
Enzyme
Mol. Mass.:
42015.38
Organism:
Homo sapiens (Human)
Description:
P31391
Residue:
388
Sequence:
MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQRVLCLRCCLLEGAGGAEEEPLDYYATALKSKGGAGCMCPPLPCQQEALQPEPGRKRIPLTRTTTF
  
Inhibitor
Name:
BDBM50159410
Synonyms:
CHEMBL404819 | Des-AA1,2,5-[D-Trp8,IAmp9,(NalphaMe)Cys14]SRIF-Lys
Type:
Small organic molecule
Emp. Form.:
C81H110N16O16S2
Mol. Mass.:
1627.968
SMILES:
CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@H](N(C)C(=O)[C@H](CO)NC(=O)[C@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](NC2=O)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(O)=O)cc1
Structure:
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