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TargetDopamine receptor
LigandBDBM50166030
Substrate/Competitorn/a
Meas. Tech.ChEMBL_303136
Ki 9.3±n/a nM
Citation Ding, KChen, JJi, MWu, XVarady, JYang, CYLu, YDeschamps, JRLevant, BWang, S Enantiomerically pure hexahydropyrazinoquinolines as potent and selective dopamine 3 subtype receptor ligands. J Med Chem48:3171-81 (2005) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Dopamine receptor
Name:Dopamine receptor D2 and D3
Synonyms:D(3) dopamine receptor | DOPAMINE D3 | DRD3 | Dopamine D3 receptor
Type:Protein
Mol. Mass.:49540.58
Organism:Rattus norvegicus (Rat)
Description:P19020
Residue:446
Sequence:
MAPLSQISTHLNSTCGAENSTGVNRARPHAYYALSYCALILAIIFGNGLVCAAVLRERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPSI
CSISNPDFVIYSSVVSFYVPFGVTVLVYARIYIVLRQRQRKRILTRQNSQCISIRPGFPQ
QSSCLRLHPIRQFSIRARFLSDATGQMEHIEDKQYPQKCQDPLLSHLQPPSPGQTHGGLK
RYYSICQDTALRHPSLEGGAGMSPVERTRNSLSPTMAPKLSLEVRKLSNGRLSTSLRLGP
LQPRGVPLREKKATQMVVIVLGAFIVCWLPFFLTHVLNTHCQACHVSPELYRATTWLGYV
NSALNPVIYTTFNVEFRKAFLKILSC
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50166030
NameBDBM50166030
Synonyms:CHEMBL371200 | Naphthalene-2-carboxylic acid [4-((S)-7-methoxy-1,2,4,4a,5,6-hexahydro-pyrazino[1,2-a]quinolin-3-yl)-butyl]-amide
TypeSmall organic molecule
Emp. Form.C28H33N3O2
Mol. Mass.443.5805
SMILESCOc1cccc2N3CCN(CCCCNC(=O)c4ccc5ccccc5c4)C[C@@H]3CCc12
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a