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Target
Procathepsin L
Ligand
BDBM50167289
Substrate
n/a
Meas. Tech.
ChEMBL_302893 (CHEMBL830209)
Ki
0.025000±n/a nM
Citation
 Barrett, DG; Deaton, DN; Hassell, AM; McFadyen, RB; Miller, AB; Miller, LR; Payne, JA; Shewchuk, LM; Willard, DH; Wright, LL Acyclic cyanamide-based inhibitors of cathepsin K. Bioorg Med Chem Lett 15:3039-43 (2005) [PubMed]  Article 
Target
Name:
Procathepsin L
Synonyms:
CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Homo sapiens (Human)
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM50167289
Synonyms:
(1S)-2-cyclohexyl-1-methylethyl 2-cyano-2-methylhydrazinecarboxylate | CHEMBL190121
Type:
Small organic molecule
Emp. Form.:
C12H21N3O2
Mol. Mass.:
239.314
SMILES:
C[C@@H](CC1CCCCC1)OC(=O)NN(C)C#N
Structure:
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