Reaction Details Report a problem with these data
Target
Basic phospholipase A2 PLA-A
Ligand
BDBM50148911
Substrate
n/a
Meas. Tech.
ChEMBL_305905 (CHEMBL832620)
IC50
2500±n/a nM
Citation
 Khanum, SA; Murari, SK; Vishwanth, BS; Shashikanth, S Synthesis of benzoyl phenyl benzoates as effective inhibitors for phospholipase A2 and hyaluronidase enzymes. Bioorg Med Chem Lett 15:4100-4 (2005) [PubMed]  Article 
Target
Name:
Basic phospholipase A2 PLA-A
Synonyms:
PA2BA_PROFL | Phospholipase A2 isozyme PLA-A
Type:
PROTEIN
Mol. Mass.:
14058.15
Organism:
Trimeresurus flavoviridis
Description:
ChEMBL_305905
Residue:
122
Sequence:
HLLQFRKMIKKMTGKEPIVSYAFYGCYCGKGGRGKPKDATDRCCFVHDCCYEKVTGCDPKWSYYTYSLEDGDIVCEGDPYCTKVKCECDKKAAICFRDNLKTYKNRYMTFPDIFCTDPTEGC
  
Inhibitor
Name:
BDBM50148911
Synonyms:
(3beta)-3-hydroxyurs-12-en-28-oic acid | 3beta-hydroxyurs-12-en-28-oic acid | CHEMBL169 | Ursolic acid | malol | prunol | urson
Type:
Small organic molecule
Emp. Form.:
C30H48O3
Mol. Mass.:
456.7003
SMILES:
C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2[C@H]1C)C(O)=O |r,c:9|
Structure:
Search PDB for entries with ligand similarity: