Reaction Details Report a problem with these data
Target
Cholecystokinin receptor type A
Ligand
BDBM50177867
Substrate
n/a
Meas. Tech.
ChEMBL_326510 (CHEMBL864538)
IC50
25.9±n/a nM
Citation
 Martín-Martínez, M; De la Figuera, N; Latorre, M; García-López, MT; Cenarruzabeitia, E; Del Río, J; González-Muñiz, R Conformationally constrained CCK4 analogues incorporating IBTM and BTD beta-turn mimetics. J Med Chem 48:7667-74 (2005) [PubMed]  Article 
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCKAR_RAT | Cckar | Cholecystokinin peripheral | Cholecystokinin receptor | Cholecystokinin receptor type A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49676.37
Organism:
RAT
Description:
Cholecystokinin central 0 RAT::P30551
Residue:
444
Sequence:
MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQILLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVMVVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQLSSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEEDGRTIRALLSRYSYSHMSTSAPPP
  
Inhibitor
Name:
BDBM50177867
Synonyms:
(2R,5R,11bS,1'S)-2-[Nalpha-(tert-butoxycarbonyl)-D-tryptophyl)amino]-5-[(1'-carbamoyl-2'-phenyl)ethyl]carbamoyl-3-oxo-2,3,5,6,11,11b-hexahydro-1H-indolizino-[8,7-b]indole | CHEMBL198902
Type:
Small organic molecule
Emp. Form.:
C40H43N7O6
Mol. Mass.:
717.8127
SMILES:
CC(C)(C)OC(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H]1C[C@@H]2N([C@H](Cc3c2[nH]c2ccccc32)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)C1=O
Structure:
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