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Target
Bcl-2-like protein 2
Ligand
BDBM50181021
Substrate
n/a
Meas. Tech.
ChEMBL_339422 (CHEMBL866580)
IC50
26850±n/a nM
Citation
 Antuch, W; Menon, S; Chen, QZ; Lu, Y; Sakamuri, S; Beck, B; Schauer-Vukasinovic, V; Agarwal, S; Hess, S; Dömling, A Design and modular parallel synthesis of a MCR derived alpha-helix mimetic protein-protein interaction inhibitor scaffold. Bioorg Med Chem Lett 16:1740-3 (2006) [PubMed]  Article 
Target
Name:
Bcl-2-like protein 2
Synonyms:
Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271
Type:
Protein
Mol. Mass.:
20742.61
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
193
Sequence:
MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
  
Inhibitor
Name:
BDBM50181021
Synonyms:
1-biphenyl-3-ylmethyl-5-butyl-4-(2-methoxy-phenyl)-1H-imidazole | CHEMBL438445
Type:
Small organic molecule
Emp. Form.:
C27H28N2O
Mol. Mass.:
396.524
SMILES:
CCCCc1c(ncn1Cc1cccc(c1)-c1ccccc1)-c1ccccc1OC
Structure:
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