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Target
Delta-type opioid receptor
Ligand
BDBM50182943
Substrate
n/a
Meas. Tech.
ChEMBL_349388 (CHEMBL865695)
EC50
22±n/a nM
Citation
 Breslin, HJ; Cai, C; Miskowski, TA; Coutinho, SV; Zhang, SP; Hornby, P; He, W Identification of potent phenyl imidazoles as opioid receptor agonists. Bioorg Med Chem Lett 16:2505-8 (2006) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
DOR-1 | K56 | MSL-2 | OPIATE Delta | OPRD_MOUSE | Opioid receptors; mu and delta | Oprd1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40577.25
Organism:
MOUSE
Description:
P32300
Residue:
372
Sequence:
MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50182943
Synonyms:
4-((S)-2-amino-3-oxo-3-((S)-3-(4-phenyl-1H-imidazol-2-yl)-3,4-dihydroisoquinolin-2(1H)-yl)propyl)-3,5-dimethylbenzamide | CHEMBL427214
Type:
Small organic molecule
Emp. Form.:
C30H31N5O2
Mol. Mass.:
493.5994
SMILES:
Cc1cc(cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1c1nc(c[nH]1)-c1ccccc1)C(N)=O
Structure:
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