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TargetAlpha-1A adrenergic receptor
LigandBDBM56339
Substrate/Competitorn/a
Meas. Tech.ChEMBL_350835
EC50 3900±n/a nM
Citation del Olmo, EBarboza, BYbarra, MILópez-Pérez, JLCarrón, RSevilla, MABoselli, CSan Feliciano, A Vasorelaxant activity of phthalazinones and related compounds. Bioorg Med Chem Lett16:2786-90 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Alpha-1A adrenergic receptor
Name:Alpha-1A adrenergic receptor
Synonyms:Adrenaline | Adrenaline 1 | Alpha-1 adrenoreceptor | adrenergic Alpha1A
Type:Protein
Mol. Mass.:51620.15
Organism:Rattus norvegicus (Rat)
Description:P43140
Residue:466
Sequence:
MVLLSENASEGSNCTHPPAPVNISKAILLGVILGGLIIFGVLGNILVILSVACHRHLHSV
THYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMGLCII
SIDRYIGVSYPLRYPTIVTQRRGVRALLCVWVLSLVISIGPLFGWRQPAPEDETICQINE
EPGYVLFSALGSFYVPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN
VPAEGGGVSSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPD
FKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRRQSSKHALGYTL
HPPSQALEGQHRDMVRIPVGSGETFYKISKTDGVCEWKFFSSMPQGSARITVPKDQSACT
TARVRSKSFLQVCCCVGSSAPRPEENHQVPTIKIHTISLGENGEEV
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  Blast E-value cutoff:
BDBM56339
n/a
NameBDBM56339
Synonyms:4-(4-chlorobenzyl)-1(2H)-phthalazinone | 4-(4-chlorobenzyl)-2H-phthalazin-1-one | 4-[(4-chlorophenyl)methyl]-2H-phthalazin-1-one | CHEMBL63976 | MLS000547504 | SMR000113649 | cid_104452
TypeSmall organic molecule
Emp. Form.C15H11ClN2O
Mol. Mass.270.714
SMILESClc1ccc(Cc2n[nH]c(=O)c3ccccc23)cc1
Structure
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