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Target
Tyrosine-protein kinase Fgr
Ligand
BDBM4078
Substrate
n/a
Meas. Tech.
ChEMBL_343255 (CHEMBL861014)
IC50
9400±n/a nM
Citation
 Cozza, G; Bonvini, P; Zorzi, E; Poletto, G; Pagano, MA; Sarno, S; Donella-Deana, A; Zagotto, G; Rosolen, A; Pinna, LA; Meggio, F; Moro, S Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application. J Med Chem 49:2363-6 (2006) [PubMed]  Article 
Target
Name:
Tyrosine-protein kinase Fgr
Synonyms:
FGR_RAT | Fgr
Type:
PROTEIN
Mol. Mass.:
58810.13
Organism:
Rattus norvegicus
Description:
ChEMBL_343255
Residue:
517
Sequence:
MGCVFCKKLEPAPKEDVGLEGDFRSQGAEERYYPDPTQGRSSSISPQPISPAFLNVGNIRSVSGTGVTIFVALYDYEARTGDDLTFTKGEKFHILNNTEYDWWEARSLSSGRTGYVPSNYVAPVDSIQAEEWYFGKISRKDAERQLLSDGNPQGAFLIRESETTKGAYSLSIRDWDQNRGDHIKHYKIRKLDMGGYYITTRAQFESVQDLVRHYMEVNDGLCYLLTAPCMVMKPQTLGLAKDAWEIDRNSIALDRRLGTGCFGDVWLGTWNCSTKVAVKTLKPGTMSPKAFLEEAQIMKLLRHDKLVQLYAVVSEEPIYIVTEFMCYGSLLDFLKDRKGHNLMLPNLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGEHLICKIADFGLARLIVDDEYNPQQGTKFPIKWTAPEAALFGRFTVKSDVWSFGILLTELITKGRVPYPGMNNREVLEQVEHGYHMPCPPGCPVSLYEVMEQTWRLDPEERPTFEYLQSFLEDYFTSTEPQYQPGDQT
  
Inhibitor
Name:
BDBM4078
Synonyms:
6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0^{4,16}.0^{11,15}]hexadeca-1(14),4(16),5,7,11(15),12-hexaene-3,10-dione | CHEMBL6246 | ELLAGIC ACID | Elagic Acid | Ellagic acid (18) | Ellagic acid dihydrate | MLS000069632 | SMR000058244 | cid_5281855
Type:
Small organic molecule
Emp. Form.:
C14H6O8
Mol. Mass.:
302.1926
SMILES:
Oc1cc2c3c(oc(=O)c4cc(O)c(O)c(oc2=O)c34)c1O
Structure:
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