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Target
Beta-glucosidase 1
Ligand
BDBM50186732
Substrate
n/a
Meas. Tech.
ChEMBL_353429 (CHEMBL870035)
pH
6.8±n/a
Ki
>1000000±n/a nM
Comments
extracted
Citation
 Wang, RW; Qiu, XL; Bols, M; Ortega-Caballero, F; Qing, FL Synthesis and biological evaluation of glycosidase inhibitors: gem-difluoromethylenated nojirimycin analogues. J Med Chem 49:2989-97 (2006) [PubMed]  Article 
Target
Name:
Beta-glucosidase 1
Synonyms:
BGL1_ASPAC | Beta-glucosidase
Type:
PROTEIN
Mol. Mass.:
93031.91
Organism:
Aspergillus aculeatus
Description:
ChEMBL_353429
Residue:
860
Sequence:
MKLSWLEAAALTAASVVSADELAFSPPFYPSPWANGQGEWAEAYQRAVAIVSQMTLDEKVNLTTGTGWELEKCVGQTGGVPRLNIGGMCLQDSPLGIRDSDYNSAFPAGVNVAATWDKNLAYLRGQAMGQEFSDKGIDVQLGPAAGPLGRSPDGGRNWEGFSPDPALTGVLFAETIKGIQDAGVVATAKHYILNEQEHFRQVAEAAGYGFNISDTISSNVDDKTIHEMYLWPFADAVRAGVGAIMCSYNQINNSYGCQNSYTLNKLLKAELGFQGFVMSDWGAHHSGVGSALAGLDMSMPGDITFDSATSFWGTNLTIAVLNGTVPQWRVDDMAVRIMAAYYKVGRDRLYQPPNFSSWTRDEYGFKYFYPQEGPYEKVNHFVNVQRNHSEVIRKLGADSTVLLKNNNALPLTGKERKVAILGEDAGSNSYGANGCSDRGCDNGTLAMAWGSGTAEFPYLVTPEQAIQAEVLKHKGSVYAITDNWALSQVETLAKQASVSLVFVNSDAGEGYISVDGNEGDRNNLTLWKNGDNLIKAAANNCNNTIVVIHSVGPVLVDEWYDHPNVTAILWAGLPGQESGNSLADVLYGRVNPGAKSPFTWGKTREAYGDYLVRELNNGNGAPQDDFSEGVFIDYRGFDKRNETPIYEFGHGLSYTTFNYSGLHIQVLNASSNAQVATETGAAPTFGQVGNASDYVYPEGLTRISKFIYPWLNSTDLKASSGDPYYGVDTAEHVPEGATDGSPQPVLPAGGGSGGNPRLYDELIRVSVTVKNTGRVAGDAVPQLYVSLGGPNEPKVVLRKFDRLTLKPSEETVWTTTLTRRDLSNWDVAAQDWVITSYPKKVHVGSSSRQLPLHAALPKVQ
  
Inhibitor
Name:
BDBM50186732
Synonyms:
CHEMBL206628 | D-1,4,6-trideoxy-4,4-difluoronojirimycin
Type:
Small organic molecule
Emp. Form.:
C6H11F2NO2
Mol. Mass.:
167.1538
SMILES:
C[C@H]1NC[C@H](O)[C@@H](O)C1(F)F
Structure:
Search PDB for entries with ligand similarity: