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Target
Adenosine receptor A3
Ligand
BDBM50001493
Substrate
n/a
Meas. Tech.
ChEMBL_364157 (CHEMBL870209)
Ki
92600±n/a nM
Citation
 Kalla, RV; Elzein, E; Perry, T; Li, X; Palle, V; Varkhedkar, V; Gimbel, A; Maa, T; Zeng, D; Zablocki, J Novel 1,3-disubstituted 8-(1-benzyl-1H-pyrazol-4-yl) xanthines: high affinity and selective A2B adenosine receptor antagonists. J Med Chem 49:3682-92 (2006) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50001493
Synonyms:
3-Propyl-3,7-dihydro-purine-2,6-dione | 3-Propyl-3,7-dihydro-purine-2,6-dione(enprofylline) | 3-Propylxanthine (enprofylline) | CHEMBL279898 | ENPROFYLLINE
Type:
Small organic molecule
Emp. Form.:
C8H10N4O2
Mol. Mass.:
194.1906
SMILES:
CCCn1c2nc[nH]c2c(=O)[nH]c1=O
Structure:
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