Reaction Details Report a problem with these data
Target
Fatty acid-binding protein, adipocyte
Ligand
BDBM50192462
Substrate
n/a
Meas. Tech.
ChEMBL_381687 (CHEMBL869163)
Ki
2.5±n/a nM
Citation
 McDonnell, PA; Constantine, KL; Goldfarb, V; Johnson, SR; Sulsky, R; Magnin, DR; Robl, JA; Caulfield, TJ; Parker, RA; Taylor, DS; Adam, LP; Metzler, WJ; Mueller, L; Farmer, BT NMR structure of a potent small molecule inhibitor bound to human keratinocyte fatty acid-binding protein. J Med Chem 49:5013-7 (2006) [PubMed]  Article 
Target
Name:
Fatty acid-binding protein, adipocyte
Synonyms:
A-FABP | AFABP | ALBP | Adipocyte lipid-binding protein | FABP4 | FABP4_HUMAN | Fatty acid binding protein adipocyte | Fatty acid-binding protein 4 | Fatty acid-binding protein 4 (FABP4)
Type:
Enzyme
Mol. Mass.:
14719.23
Organism:
Homo sapiens (Human)
Description:
P15090
Residue:
132
Sequence:
MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTFKNTEISFILGQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLVVECVMKGVTSTRVYERA
  
Inhibitor
Name:
BDBM50192462
Synonyms:
(S)-2-(2,3-bis(2-chlorobenzyloxy)phenyl)-2-hydroxyacetic acid | CHEMBL378857
Type:
Small organic molecule
Emp. Form.:
C22H18Cl2O5
Mol. Mass.:
433.281
SMILES:
O[C@H](C(O)=O)c1cccc(OCc2ccccc2Cl)c1OCc1ccccc1Cl
Structure:
Search PDB for entries with ligand similarity: