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Target
D(3) dopamine receptor
Ligand
BDBM50198269
Substrate
n/a
Meas. Tech.
ChEMBL_453346 (CHEMBL902500)
EC50
248±n/a nM
Citation
 Grundt, P; Husband, SL; Luedtke, RR; Taylor, M; Newman, AH Analogues of the dopamine D2 receptor antagonist L741,626: Binding, function, and SAR. Bioorg Med Chem Lett 17:745-9 (2007) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50198269
Synonyms:
3-((4-(4-chlorophenyl)-4-methoxypiperidin-1-yl)methyl)-1H-indole | CHEMBL246438
Type:
Small organic molecule
Emp. Form.:
C21H23ClN2O
Mol. Mass.:
354.873
SMILES:
COC1(CCN(Cc2c[nH]c3ccccc23)CC1)c1ccc(Cl)cc1
Structure:
Search PDB for entries with ligand similarity: