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TargetSphingosine 1-phosphate receptor 5
LigandBDBM50198836
Substrate/Competitorn/a
Meas. Tech.ChEMBL_432839
EC50 33±n/a nM
Citation Foss, FWSnyder, AHDavis, MDRouse, MOkusa, MDLynch, KRMacdonald, TL Synthesis and biological evaluation of gamma-aminophosphonates as potent, subtype-selective sphingosine 1-phosphate receptor agonists and antagonists. Bioorg Med Chem15:663-77 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Sphingosine 1-phosphate receptor 5
Name:Sphingosine 1-phosphate receptor
Synonyms:Endothelial differentiation sphingolipid G-protein-coupled receptor 8 | S1P5 | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-8
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:41796.42
Organism:Homo sapiens (Human)
Description:n/a
Residue:398
Sequence:
MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLV
LGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALT
ASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLD
ACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRA
RRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSL
LNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLDGSF
SGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD
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  Blast E-value cutoff:
BDBM50198836
NameBDBM50198836
Synonyms:CHEMBL389033 | [3-amino-3-(3-octylphenylcarbamoyl)propyl]-phosphonic acid
TypeSmall organic molecule
Emp. Form.C18H31N2O4P
Mol. Mass.370.4235
SMILESCCCCCCCCc1cccc(NC(=O)[C@H](N)CCP(O)(O)=O)c1
Structure
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n/a