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TargetSphingosine 1-Phosphate Receptor 4
LigandBDBM50198836
Substrate/Competitorn/a
Meas. Tech.ChEMBL_432838
EC50 6100±n/a nM
Citation Foss, FWSnyder, AHDavis, MDRouse, MOkusa, MDLynch, KRMacdonald, TL Synthesis and biological evaluation of gamma-aminophosphonates as potent, subtype-selective sphingosine 1-phosphate receptor agonists and antagonists. Bioorg Med Chem15:663-77 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Sphingosine 1-Phosphate Receptor 4
Name:Sphingosine 1-phosphate receptor
Synonyms:EDG6 | Endothelial differentiation G-protein coupled receptor 6 | S1P receptor 4 | S1P receptor Edg-6 | S1P4 | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-6 | Sphingosine-1-phosphate receptor 4 | sphingosine-1-phosphate 4 S1P4
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:41647.39
Organism:Homo sapiens (Human)
Description:n/a
Residue:384
Sequence:
MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLV
VLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFL
REGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLP
LLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRP
AARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNS
AVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDS
FRGSRSLSFRMREPLSSISSVRSI
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  Blast E-value cutoff:
BDBM50198836
NameBDBM50198836
Synonyms:CHEMBL389033 | [3-amino-3-(3-octylphenylcarbamoyl)propyl]-phosphonic acid
TypeSmall organic molecule
Emp. Form.C18H31N2O4P
Mol. Mass.370.4235
SMILESCCCCCCCCc1cccc(NC(=O)[C@H](N)CCP(O)(O)=O)c1
Structure
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n/a