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Target
Peroxisome proliferator-activated receptor gamma
Ligand
BDBM50200404
Substrate
n/a
Meas. Tech.
ChEMBL_453678 (CHEMBL885679)
EC50
360±n/a nM
Citation
 Cantin, LD; Liang, S; Ogutu, H; Iwuagwu, CI; Boakye, K; Bullock, WH; Burns, M; Clark, R; Claus, T; delaCruz, FE; Daly, M; Ehrgott, FJ; Johnson, JS; Keiper, C; Livingston, JN; Schoenleber, RW; Shapiro, J; Town, C; Yang, L; Tsutsumi, M; Ma, X Indanylacetic acid derivatives carrying aryl-pyridyl and aryl-pyrimidinyl tail groups--new classes of PPAR gamma/delta and PPAR alpha/gamma/delta agonists. Bioorg Med Chem Lett 17:1056-61 (2007) [PubMed]  Article 
Target
Name:
Peroxisome proliferator-activated receptor gamma
Synonyms:
Nr1c3 | Nuclear receptor subfamily 1 group C member 3 | PPAR-gamma | PPARG_MOUSE | Pparg
Type:
PROTEIN
Mol. Mass.:
57593.55
Organism:
Mus musculus
Description:
ChEMBL_1453700
Residue:
505
Sequence:
MGETLGDSPVDPEHGAFADALPMSTSQEITMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISAPHYEDIPFTRADPMVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNRPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKNIPGFINLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKNLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKVLQKMTDLRQIVTEHVQLLHVIKKTETDMSLHPLLQEIYKDLY
  
Inhibitor
Name:
BDBM50200404
Synonyms:
(S)-2-(5-(3-((2-(4-ethylphenyl)-5-fluoropyrimidin-4-yl)(methyl)amino)propoxy)-2,3-dihydro-1H-inden-1-yl)acetic acid | CHEMBL430182
Type:
Small organic molecule
Emp. Form.:
C27H30FN3O3
Mol. Mass.:
463.5438
SMILES:
CCc1ccc(cc1)-c1ncc(F)c(n1)N(C)CCCOc1ccc2[C@H](CC(O)=O)CCc2c1
Structure:
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