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Target
Ornithine decarboxylase
Ligand
BDBM50202558
Substrate
n/a
Meas. Tech.
ChEMBL_423773 (CHEMBL853712)
IC50
3400±n/a nM
Citation
 Maiti, A; Cuendet, M; Kondratyuk, T; Croy, VL; Pezzuto, JM; Cushman, M Synthesis and cancer chemopreventive activity of zapotin, a natural product from Casimiroa edulis. J Med Chem 50:350-5 (2007) [PubMed]  Article 
Target
Name:
Ornithine decarboxylase
Synonyms:
DCOR_HUMAN | ODC | ODC1
Type:
PROTEIN
Mol. Mass.:
51136.54
Organism:
Homo sapiens (Human)
Description:
ChEMBL_423773
Residue:
461
Sequence:
MNNFGNEEFDCHFLDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALPRVTPFYAVKCNDSKAIVKTLAATGTGFDCASKTEIQLVQSLGVPPERIIYANPCKQVSQIKYAANNGVQMMTFDSEVELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLRTSRLLLERAKELNIDVVGVSFHVGSGCTDPETFVQAISDARCVFDMGAEVGFSMYLLDIGGGFPGSEDVKLKFEEITGVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKIVLKEQTGSDDEDESSEQTFMYYVNDGVYGSFNCILYDHAHVKPLLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCDLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPTIYYVMSGPAWQLMQQFQNPDFPPEVEEQDASTLPVSCAWESGMKRHRAACASASINV
  
Inhibitor
Name:
BDBM50202558
Synonyms:
5,6,2',6'-tetramethoxyflavone | CHEMBL375582
Type:
Small organic molecule
Emp. Form.:
C19H18O6
Mol. Mass.:
342.3426
SMILES:
COc1ccc2oc(cc(=O)c2c1OC)-c1c(OC)cccc1OC
Structure:
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