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Target
D(4) dopamine receptor
Ligand
BDBM50203383
Substrate
n/a
Meas. Tech.
ChEMBL_438238 (CHEMBL887347)
Ki
11±n/a nM
Citation
 Carato, P; Graulich, A; Jensen, N; Roth, BL; Liégeois, JF Synthesis and in vitro binding studies of substituted piperidine naphthamides. Part I: Influence of the substitution on the basic nitrogen and the position of the amide on the affinity for D2L, D4.2, and 5-HT2A receptors. Bioorg Med Chem Lett 17:1565-9 (2007) [PubMed]  Article 
Target
Name:
D(4) dopamine receptor
Synonyms:
D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor
Type:
Enzyme
Mol. Mass.:
48373.19
Organism:
Homo sapiens (Human)
Description:
P21917
Residue:
419
Sequence:
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
  
Inhibitor
Name:
BDBM50203383
Synonyms:
CHEMBL228972 | N-(1-benzylpiperidin-4-yl)-2-naphthamide | N-(1-benzylpiperidine-4-yl)-2-naphthamide
Type:
Small organic molecule
Emp. Form.:
C23H24N2O
Mol. Mass.:
344.4495
SMILES:
O=C(NC1CCN(Cc2ccccc2)CC1)c1ccc2ccccc2c1
Structure:
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