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TargetNociceptin/mu opioid receptor
LigandBDBM50206660
Substrate/Competitorn/a
Meas. Tech.ChEMBL_438449
Ki 3000±n/a nM
Citation Lee, YSNyberg, JMoye, SAgnes, RSDavis, PMa, SWLai, JPorreca, FVardanyan, RHruby, VJ Understanding the structural requirements of 4-anilidopiperidine analogues for biological activities at mu and delta opioid receptors. Bioorg Med Chem Lett17:2161-5 (2007) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Nociceptin/mu opioid receptor
Name:Nociceptin/mu opioid receptor
Synonyms:MOR-1 | MUOR1 | Mu-type opioid receptor | Mu-type opioid receptor (MOR) | OPIATE Mu | Opiate non-selective | Opioid receptor B
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:44503.11
Organism:Rattus norvegicus (rat)
Description:Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor.
Residue:398
Sequence:
MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
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BDBM50206660
NameBDBM50206660
Synonyms:CHEMBL231049 | N-(1-(3-amino-3-p-tolylpropanoyl)piperidin-4-yl)-N-phenylpropionamide
TypeSmall organic molecule
Emp. Form.C24H31N3O2
Mol. Mass.393.5218
SMILESCCC(=O)N(C1CCN(CC1)C(=O)CC(N)c1ccc(C)cc1)c1ccccc1 |w:14.15|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a