Reaction Details Report a problem with these data
Target
Fatty acid-binding protein 5
Ligand
BDBM50212881
Substrate
n/a
Meas. Tech.
ChEMBL_455935 (CHEMBL887936)
Ki
830±n/a nM
Citation
 Sulsky, R; Magnin, DR; Huang, Y; Simpkins, L; Taunk, P; Patel, M; Zhu, Y; Stouch, TR; Bassolino-Klimas, D; Parker, R; Harrity, T; Stoffel, R; Taylor, DS; Lavoie, TB; Kish, K; Jacobson, BL; Sheriff, S; Adam, LP; Ewing, WR; Robl, JA Potent and selective biphenyl azole inhibitors of adipocyte fatty acid binding protein (aFABP). Bioorg Med Chem Lett 17:3511-5 (2007) [PubMed]  Article 
Target
Name:
Fatty acid-binding protein 5
Synonyms:
FABP5 | FABP5_HUMAN | Fatty acid binding protein epidermal | Fatty acid-binding protein 5 (FABP5)
Type:
Enzyme
Mol. Mass.:
15164.79
Organism:
Homo sapiens (Human)
Description:
Q01469
Residue:
135
Sequence:
MATVQQLEGRWRLVDSKGFDEYMKELGVGIALRKMGAMAKPDCIITCDGKNLTIKTESTLKTTQFSCTLGEKFEETTADGRKTQTVCNFTDGALVQHQEWDGKESTITRKLKDGKLVVECVMNNVTCTRIYEKVE
  
Inhibitor
Name:
BDBM50212881
Synonyms:
CHEMBL396698 | [2'-(1-methyl-4,5-diphenyl-1H-imidazol-2-yl)-biphenyl-3-yloxy]-acetic acid
Type:
Small organic molecule
Emp. Form.:
C30H24N2O3
Mol. Mass.:
460.5232
SMILES:
Cn1c(nc(c1-c1ccccc1)-c1ccccc1)-c1ccccc1-c1cccc(OCC(O)=O)c1
Structure:
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