Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50265409
Substrate
n/a
Meas. Tech.
ChEMBL_497301 (CHEMBL995863)
Ki
294±n/a nM
Citation
 Giorgi, I; Biagi, G; Bianucci, AM; Borghini, A; Livi, O; Leonardi, M; Pietra, D; Calderone, V; Martelli, A N6-1,3-diphenylurea derivatives of 2-phenyl-9-benzyladenines and 8-azaadenines: synthesis and biological evaluation as allosteric modulators of A2A adenosine receptors. Eur J Med Chem 43:1639-47 (2008) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50265409
Synonyms:
CHEMBL496985 | N6-[(4-Amino)-phenyl]-9-benzyl-2-phenyladenine
Type:
Small organic molecule
Emp. Form.:
C24H20N6
Mol. Mass.:
392.4558
SMILES:
Nc1ccc(Nc2nc(nc3n(Cc4ccccc4)cnc23)-c2ccccc2)cc1
Structure:
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