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Target
Lysophosphatidic acid receptor 2
Ligand
BDBM50271763
Substrate
n/a
Meas. Tech.
ChEMBL_556426 (CHEMBL955643)
IC50
21.8±n/a nM
Citation
 Fells, JI; Tsukahara, R; Fujiwara, Y; Liu, J; Perygin, DH; Osborne, DA; Tigyi, G; Parrill, AL Identification of non-lipid LPA3 antagonists by virtual screening. Bioorg Med Chem 16:6207-17 (2008) [PubMed]  Article 
Target
Name:
Lysophosphatidic acid receptor 2
Synonyms:
EDG4 | LPA receptor 2 | LPA-2 | LPA2 | LPAR2 | LPAR2_HUMAN | Lysophosphatidic acid receptor 2 | Lysophosphatidic acid receptor Edg-4
Type:
PROTEIN
Mol. Mass.:
39103.44
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1451385
Residue:
351
Sequence:
MVIMGQCYYNETIGFFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRLLCCACLRQSTRESVHYTSSAQGGASTRIMLPENGHPLMDSTL
  
Inhibitor
Name:
BDBM50271763
Synonyms:
3-[3-(3-Carboxy-acryloylamino)-phenylcarbamoyl]-acrylic acid | 4,4'-(1,3-phenylenebis(azanediyl))bis(4-oxobut-2-enoic acid) | CHEMBL519002
Type:
Small organic molecule
Emp. Form.:
C14H12N2O6
Mol. Mass.:
304.2549
SMILES:
OC(=O)\C=C\C(=O)Nc1cccc(NC(=O)\C=C\C(O)=O)c1
Structure:
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