Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50244059
Substrate
n/a
Meas. Tech.
ChEMBL_554821 (CHEMBL953974)
EC50
3.2±n/a nM
Citation
 Pagé, D; Balaux, E; Boisvert, L; Liu, Z; Milburn, C; Tremblay, M; Wei, Z; Woo, S; Luo, X; Cheng, YX; Yang, H; Srivastava, S; Zhou, F; Brown, W; Tomaszewski, M; Walpole, C; Hodzic, L; St-Onge, S; Godbout, C; Salois, D; Payza, K; Payza, K Novel benzimidazole derivatives as selective CB2 agonists. Bioorg Med Chem Lett 18:3695-700 (2008) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50244059
Synonyms:
2-(4-ethoxybenzyl)-1-(cyclopropylmethyl)-N-methyl-N-propyl-1H-benzo[d]imidazole-5-carboxamide | CHEMBL454607
Type:
Small organic molecule
Emp. Form.:
C25H31N3O2
Mol. Mass.:
405.5325
SMILES:
CCCN(C)C(=O)c1ccc2n(CC3CC3)c(Cc3ccc(OCC)cc3)nc2c1
Structure:
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