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Target
Adenosine kinase
Ligand
BDBM50252014
Substrate
n/a
Meas. Tech.
ChEMBL_491790 (CHEMBL937861)
Ki
7000±n/a nM
Citation
 Kim, YA; Sharon, A; Chu, CK; Rais, RH; Al Safarjalani, ON; Naguib, FN; el Kouni, MH Structure-activity relationships of 7-deaza-6-benzylthioinosine analogues as ligands of Toxoplasma gondii adenosine kinase. J Med Chem 51:3934-45 (2008) [PubMed]  Article 
Target
Name:
Adenosine kinase
Synonyms:
ADK_TOXGO | AK
Type:
PROTEIN
Mol. Mass.:
38353.04
Organism:
Toxoplasma gondii
Description:
ChEMBL_629062
Residue:
363
Sequence:
MAVDSSNSATGPMRVFAIGNPILDLVAEVPSSFLDEFFLKRGDATLATPEQMRIYSTLDQFNPTSLPGGSALNSVRVVQKLLRKPGSAGYMGAIGDDPRGQVLKELCDKEGLATRFMVAPGQSTGVCAVLINEKERTLCTHLGACGSFRLPEDWTTFASGALIFYATAYTLTATPKNALEVAGYAHGIPNAIFTLNLSAPFCVELYKDAMQSLLLHTNILFGNEEEFAHLAKVHNLVAAEKTALSTANKEHAVEVCTGALRLLTAGQNTGATKLVVMTRGHNPVIAAEQTADGTVVVHEVGVPVVAAEKIVDTNGAGDAFVGGFLYALSQGKTVKQCIMCGNACAQDVIQHVGFSLSFTSLPC
  
Inhibitor
Name:
BDBM50252014
Synonyms:
4-[(4-Methoxycarbonylbenzyl)thio]-7-(beta-D-ribofuranosyl)-7Hpyrrolo[2,3-d]pyrimidine | CHEMBL518458
Type:
Small organic molecule
Emp. Form.:
C20H21N3O6S
Mol. Mass.:
431.462
SMILES:
COC(=O)c1ccc(CSc2ncnc3n(ccc23)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)cc1 |r|
Structure:
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