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TargetAGTR1
LigandBDBM50141059
Substrate/Competitorn/a
Meas. Tech.ChEMBL_488660
Ki 2.1±n/a nM
Citation Wallinder, CBotros, MRosenström, UGuimond, MOBeaudry, HNyberg, FGallo-Payet, NHallberg, AAlterman, M Selective angiotensin II AT2 receptor agonists: Benzamide structure-activity relationships. Bioorg Med Chem16:6841-9 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
AGTR1
Name:Angiotensin II receptor (AT-1) type-1
Synonyms:ANGIOTENSIN AT1 | Angiotensin II AT1 | Angiotensin II AT1A | Angiotensin II receptor (AT-1) type-1 | Type-1A angiotensin II receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:40910.53
Organism:RAT
Description:ANGIOTENSIN AT1 AGTR1 RAT::P25095
Residue:359
Sequence:
MALNSSAEDGIKRIQDDCPKAGRHSYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIHRNVYFIENTNITVC
AFHYESRNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFR
IIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCKISDIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPKAKSHSSLSTKMSTLSYRPSDNMSSSAKKPASCFEVE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50141059
NameBDBM50141059
Synonyms:CHEMBL289614 | L-162782 | N-Butyloxycarbonyl-4'-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-5-isobutyl-biphenyl-2-sulfonic acid amide
TypeSmall organic molecule
Emp. Form.C32H40N4O4S
Mol. Mass.576.749
SMILESCCCCOC(=O)NS(=O)(=O)c1ccc(CC(C)C)cc1-c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a