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TargetBeta-2 adrenergic receptor and beta-3 adrenergic receptor
LigandBDBM50241366
Substrate/Competitorn/a
Meas. Tech.ChEMBL_514123
Kd 1.2±n/a nM
Citation Stephenson, KAWilson, AAMeyer, JHHoule, SVasdev, N Facile radiosynthesis of fluorine-18 labeled beta-blockers. Synthesis, radiolabeling, and ex vivo biodistribution of [18F]-(2S and 2R)-1-(1-fluoropropan-2-ylamino)-3-(m-tolyloxy)propan-2-ol. J Med Chem51:5093-100 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Beta-2 adrenergic receptor and beta-3 adrenergic receptor
Name:Beta-2 adrenergic receptor and beta-3 adrenergic receptor
Synonyms:ADRB2 | ADRB2R | B2AR | Beta-2 adrenergic receptor | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:n/a
Mol. Mass.:46461.69
Organism:Homo sapiens (Human)
Description:P07550
Residue:413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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  Blast E-value cutoff:
BDBM50241366
NameBDBM50241366
Synonyms:(S)-1-(isopropylamino)-3-(m-tolyloxy)propan-2-ol | (S)-1-(isopropylamino)-3-(m-tolyloxy)propan-2-ol ((2S)-toliprolol) | CHEMBL252319
TypeSmall organic molecule
Emp. Form.C13H21NO2
Mol. Mass.223.3113
SMILESCC(C)NC[C@H](O)COc1cccc(C)c1 |r|
Structure
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n/a