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Target
Neuropeptide Y receptor type 5
Ligand
BDBM50265206
Substrate
n/a
Meas. Tech.
ChEMBL_496407 (CHEMBL1001157)
IC50
250±n/a nM
Citation
 Ogino, Y; Ohtake, N; Nagae, Y; Matsuda, K; Moriya, M; Suga, T; Ishikawa, M; Kanesaka, M; Mitobe, Y; Ito, J; Kanno, T; Ishihara, A; Iwaasa, H; Ohe, T; Kanatani, A; Fukami, T Design, syntheses, and structure-activity relationships of novel NPY Y5 receptor antagonists: 2-{3-Oxospiro[isobenzofuran-1(3H),4'-piperidin]-1'-yl}benzimidazole derivatives. Bioorg Med Chem Lett 18:5010-4 (2008) [PubMed]  Article 
Target
Name:
Neuropeptide Y receptor type 5
Synonyms:
NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor
Type:
Enzyme
Mol. Mass.:
50746.64
Organism:
Homo sapiens (Human)
Description:
Q15761
Residue:
445
Sequence:
MDLELDEYYNKTLATENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALLSSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSNKENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAPERPSQENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIKKRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLVSLIHCLHM
  
Inhibitor
Name:
BDBM50265206
Synonyms:
1'-(4-methoxy-1H-benzo[d]imidazol-2-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one | CHEMBL496345
Type:
Small organic molecule
Emp. Form.:
C20H19N3O3
Mol. Mass.:
349.3832
SMILES:
COc1cccc2[nH]c(nc12)N1CCC2(CC1)OC(=O)c1ccccc21
Structure:
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