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Target
Casein kinase I isoform alpha
Ligand
BDBM50094895
Substrate
n/a
Meas. Tech.
ChEMBL_535969 (CHEMBL987143)
IC50
4000±n/a nM
Citation
 Cozza, G; Gianoncelli, A; Montopoli, M; Caparrotta, L; Venerando, A; Meggio, F; Pinna, LA; Zagotto, G; Moro, S Identification of novel protein kinase CK1 delta (CK1delta) inhibitors through structure-based virtual screening. Bioorg Med Chem Lett 18:5672-5 (2008) [PubMed]  Article 
Target
Name:
Casein kinase I isoform alpha
Synonyms:
CK1 | CKI-alpha | CSNK1A1 | Casein Kinase I | Casein kinase 1 alpha (CK1 alpha) | Casein kinase I isoform alpha/delta | KC1A_HUMAN
Type:
Serine/threonine-protein kinase
Mol. Mass.:
38936.59
Organism:
Homo sapiens (Human)
Description:
P48729
Residue:
337
Sequence:
MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAASSSGQGQQAQTPTGKQTDKTKSNMKGF
  
Inhibitor
Name:
BDBM50094895
Synonyms:
1,4-diamino-9,10-anthraquinone | 1,4-diamino-anthraquinone | 1,4-diaminoanthracene-9,10-dione | CHEMBL86771
Type:
Small organic molecule
Emp. Form.:
C14H10N2O2
Mol. Mass.:
238.2414
SMILES:
Nc1ccc(N)c2C(=O)c3ccccc3C(=O)c12
Structure:
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