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Target
Mu-type opioid receptor
Ligand
BDBM50252862
Substrate
n/a
Meas. Tech.
ChEMBL_534705 (CHEMBL982794)
Ki
15.5±n/a nM
Citation
 Ghosh, A; Luo, J; Liu, C; Weltrowska, G; Lemieux, C; Chung, NN; Lu, Y; Schiller, PW Novel opioid peptide derived antagonists containing (2S)-2-methyl-3-(2,6-dimethyl-4-carbamoylphenyl)propanoic acid [(2S)-Mdcp]. J Med Chem 51:5866-70 (2008) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50252862
Synonyms:
(5S,8S,14R)-8-Benzyl-14-[(S)-2-[3-(4-hydroxy-2,6-dimethyl-phenyl)-propionylamino]-3-(4-hydroxy-phenyl)-propionylamino]-2,7,10,13-tetraoxo-1,3,6,9,12pentaaza-cyclooctadecane-5-carboxylic acid | CHEMBL449801
Type:
Small organic molecule
Emp. Form.:
C41H51N7O10
Mol. Mass.:
801.8845
SMILES:
Cc1cc(O)cc(C)c1CCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CCCCNC(=O)NC[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC1=O)C(O)=O |r|
Structure:
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