Reaction Details Report a problem with these data
Target
Arylsulfatase
Ligand
BDBM50098109
Substrate
n/a
Meas. Tech.
ChEMBL_544783 (CHEMBL1011099)
Ki
130±n/a nM
Citation
 Bojarová, P; Williams, SJ Aryl sulfamates are broad spectrum inactivators of sulfatases: effects on sulfatases from various sources. Bioorg Med Chem Lett 19:477-80 (2008) [PubMed]  Article 
Target
Name:
Arylsulfatase
Synonyms:
ARS_PSEAE | atsA
Type:
PROTEIN
Mol. Mass.:
59936.42
Organism:
Pseudomonas aeruginosa
Description:
ChEMBL_879574
Residue:
536
Sequence:
MSKRPNFLVIVADDLGFSDIGAFGGEIATPNLDALAIAGLRLTDFHTASTCSPTRSMLLTGTDHHIAGIGTMAEALTPELEGKPGYEGHLNERVVALPELLREAGYQTLMAGKWHLGLKPEQTPHARGFERSFSLLPGAANHYGFEPPYDESTPRILKGTPALYVEDERYLDTLPEGFYSSDAFGDKLLQYLKERDQSRPFFAYLPFSAPHWPLQAPREIVEKYRGRYDAGPEALRQERLARLKELGLVEADVEAHPVLALTREWEALEDEERAKSARAMEVYAAMVERMDWNIGRVVDYLRRQGELDNTFVLFMSDNGAEGALLEAFPKFGPDLLGFLDRHYDNSLENIGRANSYVWYGPRWAQAATAPSRLYKAFTTQGGIRVPALVRYPRLSRQGAISHAFATVMDVTPTLLDLAGVRHPGKRWRGREIAEPRGRSWLGWLSGETEAAHDENTVTGWELFGMRAIRQGDWKAVYLPAPVGPATWQLYDLARDPGEIHDLADSQPGKLAELIEHWKRYVSETGVVEGASPFLVR
  
Inhibitor
Name:
BDBM50098109
Synonyms:
3-nitrophenyl sulfamate | CHEMBL283560 | Sulfamic acid 3-nitro-phenyl ester
Type:
Small organic molecule
Emp. Form.:
C6H6N2O5S
Mol. Mass.:
218.187
SMILES:
NS(=O)(=O)Oc1cccc(c1)[N+]([O-])=O
Structure:
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