Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM50265985
Substrate
n/a
Meas. Tech.
ChEMBL_540180 (CHEMBL1029809)
Ki
281±n/a nM
Citation
 Cole, AG; Stauffer, TM; Rokosz, LL; Metzger, A; Dillard, LW; Zeng, W; Henderson, I Synthesis of 2-amino-5-benzoyl-4-(2-furyl)thiazoles as adenosine A(2A) receptor antagonists. Bioorg Med Chem Lett 19:378-81 (2008) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM50265985
Synonyms:
CHEMBL460172 | N-(2-(5-benzoyl-4-(furan-2-yl)thiazol-2-ylamino)ethyl)acetamide
Type:
Small organic molecule
Emp. Form.:
C18H17N3O3S
Mol. Mass.:
355.411
SMILES:
CC(=O)NCCNc1nc(-c2ccco2)c(s1)C(=O)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: