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Target
Arylamine N-acetyltransferase 2
Ligand
BDBM50275068
Substrate
n/a
Meas. Tech.
ChEMBL_494097 (CHEMBL942269)
IC50
11800±n/a nM
Citation
 Russell, AJ; Westwood, IM; Crawford, MH; Robinson, J; Kawamura, A; Redfield, C; Laurieri, N; Lowe, ED; Davies, SG; Sim, E Selective small molecule inhibitors of the potential breast cancer marker, human arylamine N-acetyltransferase 1, and its murine homologue, mouse arylamine N-acetyltransferase 2. Bioorg Med Chem 17:905-18 (2009) [PubMed]  Article 
Target
Name:
Arylamine N-acetyltransferase 2
Synonyms:
ARY2_MOUSE | Aac2 | Nat2
Type:
PROTEIN
Mol. Mass.:
33697.98
Organism:
Mus musculus
Description:
ChEMBL_1347887
Residue:
290
Sequence:
MDIEAYFERIGYQSTRSKLDLKTLTEILQHQIRAIPFENLNIHCGESMELSLEAIFDQIVRKKRGGWCLQVNHLLYWALTKLGFETTMLGGYVFNTPANKYSSGMIHLLVQVTISGKDYIVDAGFGRSYQMWEPLELTSGKDQPQVPAIFRLTEENGTWYLDQIRREQYVPNQEFINSDLLEKNKYRKIYSFTLEPRTIEDFESMNTYLQTSPASVFTSKSFCSLQTPEGVHCLVGSTLTYRRFSYKDNVDLVEFKSLTEEEIEDVLRTIFGVSLERKLVPKHGDRFFTI
  
Inhibitor
Name:
BDBM50275068
Synonyms:
(Z)-5-(2'-Fluorobenzylidene)-3-methyl-2-thioxothiazolidin-4-one | CHEMBL457709
Type:
Small organic molecule
Emp. Form.:
C11H8FNOS2
Mol. Mass.:
253.316
SMILES:
CN1C(=S)S\C(=C/c2ccccc2F)C1=O
Structure:
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