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Target
Fatty acid-binding protein, adipocyte
Ligand
BDBM50247992
Substrate
n/a
Meas. Tech.
ChEMBL_566942 (CHEMBL964125)
IC50
430±n/a nM
Citation
 Barf, T; Lehmann, F; Hammer, K; Haile, S; Axen, E; Medina, C; Uppenberg, J; Svensson, S; Rondahl, L; Lundbäck, T N-Benzyl-indolo carboxylic acids: Design and synthesis of potent and selective adipocyte fatty-acid binding protein (A-FABP) inhibitors. Bioorg Med Chem Lett 19:1745-8 (2009) [PubMed]  Article 
Target
Name:
Fatty acid-binding protein, adipocyte
Synonyms:
A-FABP | AFABP | ALBP | Adipocyte lipid-binding protein | FABP4 | FABP4_HUMAN | Fatty acid binding protein adipocyte | Fatty acid-binding protein 4 | Fatty acid-binding protein 4 (FABP4)
Type:
Enzyme
Mol. Mass.:
14719.23
Organism:
Homo sapiens (Human)
Description:
P15090
Residue:
132
Sequence:
MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTFKNTEISFILGQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLVVECVMKGVTSTRVYERA
  
Inhibitor
Name:
BDBM50247992
Synonyms:
5-propyl-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-4-carboxylic acid | CHEMBL516469
Type:
Small organic molecule
Emp. Form.:
C17H21NO2
Mol. Mass.:
271.3541
SMILES:
CCCn1c2CCCCCc2c2cccc(C(O)=O)c12
Structure:
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