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TargetAlpha-2B adrenergic receptor
LigandBDBM50250521
Substrate/Competitorn/a
Meas. Tech.ChEMBL_564353
EC50 4200±n/a nM
Citation Davis, RAFechner, GASykes, MGaravelas, APass, DMCarroll, ARAddepalli, RAvery, VMHooper, JNQuinn, RJ (-)-Dibromophakellin: an alpha2B adrenoceptor agonist isolated from the Australian marine sponge, Acanthella costata. Bioorg Med Chem17:2497-500 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Alpha-2B adrenergic receptor
Name:Alpha-2B adrenergic receptor
Synonyms:ADRA2L1 | ADRA2RL1 | Adrenergic alpha2B | Adrenergic receptor alpha | Adrenergic, alpha-2B-, receptor [Homo sapiens] | Alpha-2 adrenergic receptor subtype C2 | Alpha-2B adrenoceptor | Alpha-2B adrenoreceptor | Alpha-2BAR
Type:Enzyme
Mol. Mass.:49579.89
Organism:Homo sapiens (Human)
Description:P18089
Residue:447
Sequence:
MDHQDPYSVQATAAIAAAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADIL
VATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEY
NSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGPQPRGRPQCKLNQEAWYILASSIGS
FFAPCLIMILVYLRIYLIAKRSNRRGPRAKGGPGQGESKQPRPDHGGALASAKLPALASV
ASAREVNGHSKSTGEKEEGETPEDTGTRALPPSWAALPNSGQGQKEGVCGASPEDEAEEE
EEEEEECEPQAVPVSPASACSPPLQQPQGSRVLATLRGQVLLGRGVGAIGGQWWRRRAQL
TREKRFTFVLAVVIGVFVLCWFPFFFSYSLGAICPKHCKVPHGLFQFFFWIGYCNSSLNP
VIYTIFNQDFRRAFRRILCRPWTQTAW
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BDBM50250521
NameBDBM50250521
Synonyms:(-)-dibromophakellin | CHEMBL447696 | dibromophakellin
TypeSmall organic molecule
Emp. Form.C11H11Br2N5O
Mol. Mass.389.046
SMILESNC1=N[C@H]2n3c(Br)c(Br)cc3C(=O)N3CCC[C@]23N1 |r,t:1|
Structure
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n/a
NameBDBM50250521
Synonyms:(-)-dibromophakellin | CHEMBL447696 | dibromophakellin
TypeSmall organic molecule
Emp. Form.C11H11Br2N5O
Mol. Mass.389.046
SMILESNC1=N[C@H]2n3c(Br)c(Br)cc3C(=O)N3CCC[C@]23N1 |r,t:1|
Structure
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