Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50267637
Substrate
n/a
Meas. Tech.
ChEMBL_563546 (CHEMBL961833)
IC50
>10000±n/a nM
Citation
 Brizzi, A; Brizzi, V; Cascio, MG; Corelli, F; Guida, F; Ligresti, A; Maione, S; Martinelli, A; Pasquini, S; Tuccinardi, T; Di Marzo, V New resorcinol-anandamide"hybrids" as potent cannabinoid receptor ligands endowed with antinociceptive activity in vivo. J Med Chem 52:2506-14 (2009) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52856.55
Organism:
Rattus norvegicus (rat)
Description:
P20272
Residue:
473
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50267637
Synonyms:
11-(3,5-Dihydroxyphenoxy)undecanoic Acid (2-Hydroxyethyl)amide | CHEMBL489835
Type:
Small organic molecule
Emp. Form.:
C19H31NO5
Mol. Mass.:
353.4531
SMILES:
OCCNC(=O)CCCCCCCCCCOc1cc(O)cc(O)c1
Structure:
Search PDB for entries with ligand similarity: