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Target
Alpha-2A adrenergic receptor
Ligand
BDBM50259333
Substrate
n/a
Meas. Tech.
ChEMBL_499394 (CHEMBL1015846)
EC50
>10000±n/a nM
Citation
 Whitlock, GA; Brennan, PE; Roberts, LR; Stobie, A Potent and selective alpha1A adrenoceptor partial agonists--novel imidazole frameworks. Bioorg Med Chem Lett 19:3118-21 (2009) [PubMed]  Article 
Target
Name:
Alpha-2A adrenergic receptor
Synonyms:
ADA2A_HUMAN | ADRA2A | ADRA2R | ADRAR | Adrenergic alpha2A | Adrenergic receptor alpha | Alpha-2 adrenergic receptor subtype C10 | Alpha-2A adrenoceptor | Alpha-2A adrenoreceptor | Alpha-2AAR | alpha-2A adrenergic receptor [Homo sapiens]
Type:
Enzyme
Mol. Mass.:
48979.91
Organism:
Homo sapiens (Human)
Description:
P08913
Residue:
450
Sequence:
MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV
  
Inhibitor
Name:
BDBM50259333
Synonyms:
6-phenyl-4,5,6,7-tetra hydro-1H-benzo[d]imidazole | 6-phenyl-4,5,6,7-tetrahydro-1H-benzo[d]imidazole | CHEMBL466296
Type:
Small organic molecule
Emp. Form.:
C13H14N2
Mol. Mass.:
198.2637
SMILES:
C1Cc2nc[nH]c2CC1c1ccccc1
Structure:
Search PDB for entries with ligand similarity: