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Target
Muscarinic acetylcholine receptor M1
Ligand
BDBM50280561
Substrate
n/a
Meas. Tech.
ChEMBL_138283 (CHEMBL744240)
IC50
3690±n/a nM
Citation
 Tecle, H; Mirzadegan, T; Moos, WH; Moreland, DW; Pavia, MR; Schwarz, RD; Davis, RE A rationale for the design and synthesis of m1 selective muscarinic agonists. Bioorg Med Chem Lett 2:821-826 (1992)    Article 
Target
Name:
Muscarinic acetylcholine receptor M1
Synonyms:
ACM1_HUMAN | CHRM1 | Cholinergic receptor, muscarinic 1 | Cholinergic, muscarinic M1
Type:
Protein
Mol. Mass.:
51442.54
Organism:
Homo sapiens (Human)
Description:
P11229
Residue:
460
Sequence:
MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
  
Inhibitor
Name:
BDBM50280561
Synonyms:
1-Aza-bicyclo[2.2.1]heptan-3-one O-(1-methyl-prop-2-ynyl)-oxime | CHEMBL166537
Type:
Small organic molecule
Emp. Form.:
C10H14N2O
Mol. Mass.:
178.231
SMILES:
CC(O\N=C1/CN2CCC1C2)C#C |THB:3:4:10:8.7|
Structure:
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