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Target
Type-1 angiotensin II receptor
Ligand
BDBM50145961
Substrate
n/a
Meas. Tech.
ChEBML_36950
IC50
4±n/a nM
Citation
 Mantlo, N; Chang, RS; Siegl, P Angiotensin II receptor antagonists containing a phenylpyridine element. Bioorg Med Chem Lett 3:1693-1696 (1993)    Article 
Target
Name:
Type-1 angiotensin II receptor
Synonyms:
AGTR1 | AGTR1_RABIT | ANGIOTENSIN AT1 | Angiotensin II receptor | Angiotensin II type 1a (AT-1a) receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41009.15
Organism:
RABBIT
Description:
ANGIOTENSIN AT1 AGTR1 RABBIT::P34976
Residue:
359
Sequence:
MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE
  
Inhibitor
Name:
BDBM50145961
Synonyms:
7-Methyl-2-propyl-3-{4-[3-(2H-tetrazol-5-yl)-pyridin-4-yl]-benzyl}-3H-imidazo[4,5-b]pyridine | CHEMBL47382
Type:
Small organic molecule
Emp. Form.:
C23H22N8
Mol. Mass.:
410.4744
SMILES:
CCCc1nc2c(C)ccnc2n1Cc1ccc(cc1)-c1ccncc1-c1nnn[nH]1
Structure:
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