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Target
Type-2 angiotensin II receptor
Ligand
BDBM50145974
Substrate
n/a
Meas. Tech.
ChEBML_35408
IC50
>20000±n/a nM
Citation
 Mantlo, N; Chang, RS; Siegl, P Angiotensin II receptor antagonists containing a phenylpyridine element. Bioorg Med Chem Lett 3:1693-1696 (1993)    Article 
Target
Name:
Type-2 angiotensin II receptor
Synonyms:
AGTR2_RAT | AT2 | Agtr2 | Angiotensin II AT2 | Angiotensin II receptor | Angiotensin II type 2 (AT-2) receptor | Type-2 angiotensin II receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41346.62
Organism:
RAT
Description:
Angiotensin II AT2 0 0::P35351
Residue:
363
Sequence:
MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS
  
Inhibitor
Name:
BDBM50145974
Synonyms:
7-Methyl-2-propyl-3-{4-[2-(2H-tetrazol-5-yl)-pyridin-3-yl]-benzyl}-3H-imidazo[4,5-b]pyridine | CHEMBL47459
Type:
Small organic molecule
Emp. Form.:
C23H22N8
Mol. Mass.:
410.4744
SMILES:
CCCc1nc2c(C)ccnc2n1Cc1ccc(cc1)-c1cccnc1-c1nnn[nH]1
Structure:
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