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Target
Vitamin D3 receptor
Ligand
BDBM50200182
Substrate
n/a
Meas. Tech.
ChEBML_214154
Ki
0.025000±n/a nM
Citation
 Calverley, MJ; Binderup, L Synthesis and biological evaluation of MC 1357, a new 20-epi-23-oxa-1α,25-dihydroxy-vitamin D3 analogue with potent non-classical effects Bioorg Med Chem Lett 3:1845-1848 (1993)    Article 
Target
Name:
Vitamin D3 receptor
Synonyms:
NR1I1 | VDR | VDR_CHICK | Vitamin D receptor
Type:
PROTEIN
Mol. Mass.:
51292.53
Organism:
Gallus gallus
Description:
ChEMBL_214183
Residue:
451
Sequence:
MSELRGSWDEQQQSMAYLPDADMDTVAASTSLPDPAGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKAMFTCPFNGDCKITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKESLKPKLSEEQQKVIDTLLEAHHKTFDTTYSDFNKFRPPVRSKFSSRMATHSSSVVSQDFSSEDSNDVFGSDAFAAFPEPMEPQMFSNLDLSEESDESPSMNIELPHLPMLPHLADLVSYSIQKVIGFAKMIPGFRDLTAEDQIALLKSSAIEVIMLRSNQSFTMEDMSWTCGSNDFKYKVSDVTQAGHSMDLLEPLVKFQVGLKKLNLHEEEHVLLMAICILSPDRPGVQDTSLVESIQDRLSDILQTYIRCRHPPPGSRLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPEHSMQLTPLVLEVFGNEIS
  
Inhibitor
Name:
BDBM50200182
Synonyms:
(1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol | (1S,3R,5Z,7E)-9,10-secocholesta-5,7,10-triene-1,3,25-triol | (1alpha,3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol | (5Z,7E)-(1S,3R)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol | 1,25-DHCC | 1alpha,25(OH)2D3 | 1alpha,25-dihydroxycholecalciferol | 1alpha,25-dihydroxyvitamin D3 | CALCITRIOL | CHEMBL846
Type:
Small organic molecule
Emp. Form.:
C27H44O3
Mol. Mass.:
416.6365
SMILES:
C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C |r|
Structure:
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