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Target
Type-2 angiotensin II receptor
Ligand
BDBM50282306
Substrate
n/a
Meas. Tech.
ChEMBL_35560 (CHEMBL645745)
IC50
150±n/a nM
Citation
 Kevin, NJ; Rivero, RA; Greenlee, WJ; Chang, RS; Chen, TB Subtituted phenylthiophene benzoylsulfonamides with potent binding affinity to angiotensin II AT1 and AT2 receptors Bioorg Med Chem Lett 4:189-194 (1994)    Article 
Target
Name:
Type-2 angiotensin II receptor
Synonyms:
AGTR2_RAT | AT2 | Agtr2 | Angiotensin II AT2 | Angiotensin II receptor | Angiotensin II type 2 (AT-2) receptor | Type-2 angiotensin II receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41346.62
Organism:
RAT
Description:
Angiotensin II AT2 0 0::P35351
Residue:
363
Sequence:
MKDNFSFAATSRNITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIVVVSLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYVVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRETMSCRKSSSLREMDTFVS
  
Inhibitor
Name:
BDBM50282306
Synonyms:
3-[4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-phenyl]-5-pentyl-thiophene-2-sulfonic acid benzoylamide | CHEMBL293949
Type:
Small organic molecule
Emp. Form.:
C33H36N4O3S2
Mol. Mass.:
600.794
SMILES:
CCCCCc1cc(c(s1)S(=O)(=O)NC(=O)c1ccccc1)-c1ccc(Cn2c(CC)nc3c(C)cc(C)nc23)cc1
Structure:
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