Reaction Details Report a problem with these data
Target
Leukotriene B4 receptor 1
Ligand
BDBM50283054
Substrate
n/a
Meas. Tech.
ChEBML_98629
Ki
1.1±n/a nM
Citation
 Sawyer, J; Schmittling, EA; Bach, NJ; Baker, S; Froelich, LL; Saussy, DL; Marder, P; Jackson, WT Structural analogues of LY292728, a highly potent xanthone dicarboxylic acid leukotriene B4 receptor antagonist: spatial positioning of the secondary acid group Bioorg Med Chem Lett 4:2077-2082 (1994)    Article 
Target
Name:
Leukotriene B4 receptor 1
Synonyms:
BLT | BLT1 | BLTR | CMKRL1 | Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | GPR16 | LT4R1_HUMAN | LTB4-R 1 | LTB4R | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2RY7 | P2Y purinoceptor 7 | P2Y7
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37582.68
Organism:
Homo sapiens (Human)
Description:
Q15722
Residue:
352
Sequence:
MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNLALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVARPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAFHLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVVNLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
  
Inhibitor
Name:
BDBM50283054
Synonyms:
4-{2-(2-Carboxy-ethyl)-3-[3-(5-ethyl-4'-fluoro-2-hydroxy-biphenyl-4-yloxy)-propoxy]-phenoxy}-benzoic acid | CHEMBL262231
Type:
Small organic molecule
Emp. Form.:
C33H31FO8
Mol. Mass.:
574.5928
SMILES:
CCc1cc(c(O)cc1OCCCOc1cccc(Oc2ccc(cc2)C(O)=O)c1CCC(O)=O)-c1ccc(F)cc1
Structure:
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