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Reaction Details
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TargetAngiotensin II receptor
LigandBDBM50406795
Substrate/Competitorn/a
Meas. Tech.ChEBML_35253
IC50 5.5±n/a nM
Citation Olson, RELiu, JLalka, GKVanAtten, MKWexler, RRChiu, ATNguyen, TTMcCall, DEWong, PCTimmermans, PB Balanced angiotensin II receptor antagonists. II.1,2 4-aminomethyl- and acylaminomethylimidazoles Bioorg Med Chem Lett4:2229-2234 (1994)    Article
More Info.:Get all data from this article,  Assay Method
 
Angiotensin II receptor
Name:Angiotensin II receptor
Synonyms:AT1 | AT1AR | AT1BR | Angiotensin II AT1 | Angiotensin II receptor | Angiotensin II type 1b (AT-1b) receptor | Type-1 angiotensin II receptor (AT1)
Type:Protein
Mol. Mass.:41080.75
Organism:Homo sapiens (Human)
Description:P30556
Residue:359
Sequence:
MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK
IIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPCFEVE
Blast this sequence in BindingDB or PDB
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BDBM50406795
NameBDBM50406795
Synonyms:Cozaar | LOSARTAN POTASSIUM
TypeSmall organic molecule
Emp. Form.C22H22ClN6O
Mol. Mass.421.903
SMILESCCCCc1nc(Cl)c(CO)n1Cc1ccc(cc1)-c1ccccc1-c1nn[n-]n1
Structure
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n/a