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Target
Membrane primary amine oxidase
Ligand
BDBM50285494
Substrate
n/a
Meas. Tech.
ChEBML_200166
Ki
17000±n/a nM
Citation
 Danzin, C; Collard, JN; Marchal, P; Schirlin, D Silicon-mediated inactivation of semicarbazide-sensitive amine oxidase Bioorg Med Chem Lett 5:2363-2366 (1995)    Article 
Target
Name:
Membrane primary amine oxidase
Synonyms:
AOC3_RAT | Amine oxidase, copper containing | Aoc3 | Semicarbazide-sensitive amine oxidase/ Vascular adhesion protein 1 (SSAO/VAP-1) | Vascular adhesion protein 1 (VAP-1)
Type:
Enzyme
Mol. Mass.:
84979.78
Organism:
Rattus norvegicus (Rat)
Description:
O08590
Residue:
763
Sequence:
MTQKTTLVLLALAVITIFALVCVLLAGRSGDGGRLSQPLHCPSVLPSVQPQTHPGQSQPFADLSPEELTAVMSFLIKHLGPGLVDAAQARPSDNCVFSVELQLPAKAAALAHLDRGGPPPVREALAIIFFGGQPKPNVSELVVGPLPHPSYMRDVTVERHGGPLPYYRRPVLTREYQDIQEMIFHRELPQASGLLHHCCFYKRQGHNLLKMTTAPRGLQSGDRATWFGIYYNLSGAGFYPHPIGLELLVDHKALDPALWTIQKVFYQGRYYESLTQLEDMFEAGLVNVVLVPDNGTGGSWSLKSSVPPGRAPPLQFHPEGPRFSVQGSQVRSSLWAFSFGLGAFSGPRIFDIRFQGERVAYEISVQEAIALYGGNSPASMSTCYMDGSFGIGKYSTPLTRGVDCPYLATYVDWHFLLESQTPKTLRDAFCVFEQNQGLPLRRHHSDFYSHYFGGVVETVLVVRSVATLLNYDYVWDMVFHSNGAIEVKFHATGYITSAFFFGAGEKFGNRVAEHTLGTVHTHNAHFKVDLDVAGLKNWAWAEDLAFVPMNVPWQPEFQMQRLQVTRKLLETEEEAAFPLGNATPRYLYLASNHSNKWGHRRGYRIQILSFAGKPLPQESPIEKAFTWGRYHLAVTQRKEEEPSSSSIYNQNDPWTPTVDFTDFISNETIAGEDLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPSFYSPDSIYFRKDQDVTDCEVNSLACLSQTANCVPDLPAFSHGGFTYK
  
Inhibitor
Name:
BDBM50285494
Synonyms:
C-[(Dimethyl-phenethyl-silanyl)]-methylamine | CHEMBL77272
Type:
Small organic molecule
Emp. Form.:
C11H19NSi
Mol. Mass.:
193.3608
SMILES:
C[Si](C)(CN)CCc1ccccc1
Structure:
Search PDB for entries with ligand similarity: