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Target
Trehalase
Ligand
BDBM50286541
Substrate
n/a
Meas. Tech.
ChEBML_208276
Ki
180±n/a nM
Citation
 Yamagishi, T; Uchida, C; Ogawa, S Total synthesis of trehalase inhibitor salbostatin Bioorg Med Chem Lett 5:487-490 (1995)    Article 
Target
Name:
Trehalase
Synonyms:
Alpha,alpha-trehalase | Alpha,alpha-trehalose glucohydrolase | TREA | TREA_HUMAN | TREH
Type:
PROTEIN
Mol. Mass.:
66559.41
Organism:
Homo sapiens (Human)
Description:
ChEMBL_208276
Residue:
583
Sequence:
MPGRTWELCLLLLLGLGLGSQEALPPPCESEIYCHGELLNQVQMAKLYQDDKQFVDMPLSIAPEQVLQTFTELSRDHNHSIPREQLQAFVHEHFQAKGQELQPWTPADWKDSPQFLQKISDAKLRAWAGQLHQLWKKLGKKMKPEVLSHPERFSLIYSEHPFIVPGGRFVEFYYWDSYWVMEGLLLSEMAETVKGMLQNFLDLVKTYGHVPNGGRVYYLQRSQPPLLTLMMDCYLTHTNDTAFLQENIETLALELDFWTKNRTVSVSLEGKNYLLNRYYVPYGGPRPESYSKDVELADTLPEGDREALWAELKAGAESGWDFSSRWLIGGPNPNSLSGIRTSKLVPVDLNAFLCQAEELMSNFYSRLGNDSQATKYRILRSQRLAALNTVLWDEQTGAWFDYDLEKKKKNREFYPSNLTPLWAGCFSDPGVADKALKYLEDNRILTYQYGIPTSLQKTGQQWDFPNAWAPLQDLVIRGLAKAPLRRAQEVAFQLAQNWIRTNFDVYSQKSAMYEKYDVSNGGQPGGGGEYEVQEGFGWTNGVVLMLLDRYGDRLTSGAKLAFLEPHCLAATLLPSLLLSLLPW
  
Inhibitor
Name:
BDBM50286541
Synonyms:
6-(4,5-Dihydroxy-6-hydroxymethyl-tetrahydro-pyran-3-ylamino)-4-hydroxymethyl-cyclohex-4-ene-1,2,3-triol | CHEMBL145196
Type:
Small organic molecule
Emp. Form.:
C13H23NO8
Mol. Mass.:
321.3236
SMILES:
OCC1OCC(NC2C=C(CO)C(O)C(O)C2O)C(O)C1O |t:8|
Structure:
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