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Target
D(3) dopamine receptor
Ligand
BDBM50071960
Substrate
n/a
Meas. Tech.
ChEMBL_62290 (CHEMBL675060)
Ki
8±n/a nM
Citation
 Glase, SA; Akunne, HC; Heffner, TG; Johnson, SJ; Kesten, SR; MacKenzie, RG; Manley, PJ; Pugsley, TA; Wright, JL; Wise, LD 4-bromo-1-methoxy-N-[2-(4-aryl-1-piperazinyl)ethyl]-2-naphthalenecarboxamides: Selective dopamine D3 receptor partial agonists Bioorg Med Chem Lett 6:1361-1366 (1996)    Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50071960
Synonyms:
4-Bromo-1-methoxy-naphthalene-2-carboxylic acid {2-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-ethyl}-amide | CHEMBL287198
Type:
Small organic molecule
Emp. Form.:
C24H24BrCl2N3O2
Mol. Mass.:
537.276
SMILES:
COc1c(cc(Br)c2ccccc12)C(=O)NCCN1CCN(CC1)c1cccc(Cl)c1Cl
Structure:
Search PDB for entries with ligand similarity: