Reaction Details Report a problem with these data
Target
Adenosine deaminase
Ligand
BDBM50288073
Substrate
n/a
Meas. Tech.
ChEBML_30813
Ki
51±n/a nM
Citation
 Pragnacharyulu, PV; Lu, PJ; Abushanab, E Adenosine deaminase inhibitors. Synthesis and biological evaluation of chain modified analogs of (+)-EHNA Bioorg Med Chem Lett 6:2417-2420 (1996)    Article 
Target
Name:
Adenosine deaminase
Synonyms:
ADA | ADA_BOVIN | Adenosine aminohydrolase
Type:
Enzyme
Mol. Mass.:
40910.44
Organism:
Bos taurus (bovine)
Description:
n/a
Residue:
363
Sequence:
MAQTPAFNKPKVELHVHLDGAIKPETILYYGRKRGIALPADTPEELQNIIGMDKPLSLPEFLAKFDYYMPAIAGCREAVKRIAYEFVEMKAKDGVVYVEVRYSPHLLANSKVEPIPWNQAEGDLTPDEVVSLVNQGLQEGERDFGVKVRSILCCMRHQPSWSSEVVELCKKYREQTVVAIDLAGDETIEGSSLFPGHVKAYAEAVKSGVHRTVHAGEVGSANVVKEAVDTLKTERLGHGYHTLEDATLYNRLRQENMHFEVCPWSSYLTGAWKPDTEHPVVRFKNDQVNYSLNTDDPLIFKSTLDTDYQMTKNEMGFTEEEFKRLNINAAKSSFLPEDEKKELLDLLYKAYGMPSPASAEQCL
  
Inhibitor
Name:
BDBM50288073
Synonyms:
(E)-(2S,3R)-3-(6-Amino-purin-9-yl)-non-5-en-2-ol | 3-(6-Amino-purin-9-yl)-non-5-en-2-ol | CHEMBL81378
Type:
Small organic molecule
Emp. Form.:
C14H21N5O
Mol. Mass.:
275.3494
SMILES:
CCC\C=C\C[C@H]([C@H](C)O)n1cnc2c(N)ncnc12
Structure:
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